Cell signaling different stages are present in them as firstly reception whereby the signal molecule binds the receptor and then the signal transduction where the chemical signal results in a series of enzyme activations. Finally the response is resulting cellular responses. There are mainly classified as Intracrine, Autocrine, Juxtracrine, Paracrine and endocrine.intracrine signals are produced by target cell that stay within the target cell .Autocrine signals are produced by the target cell which are secreted and affect the target cell.Juxtacrine signals are transmitted along the cell membranes. Paracrine signals travels through the target cells in the vicinity of emitting cell. Cell signaling has the main function in the human organs it has different forms of signaling like paracrine signaling, autocrine signaling and endocrine signaling. In paracrine signaling cells are near to each other and easy to communicate through the release of chemical messengers. The signally allows the cells to locally coordinate activities with their neighbors. Endocrine signaling cells need to transmit the signals over the long distance like circulatory system.
Some of the cell signaling is responsible for some cancer and immune disorders to treat them JAK inhibitors have been proposed a drug therapy and STAT can improve the survival of patients with cancer and another drug called tofacitinib has been used for psoriasis.
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